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Carl Sagan

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Humans may crave absolute certainty; they may aspire to it; they may pretend, as partisans of certain religions do, to have attained it. But the history of science — by far the most successful claim to knowledge accessible to humans — teaches that the most we can hope for is successive improvement in our understanding, learning from our mistakes, an asymptotic approach to the Universe, but with the proviso that absolute certainty will always elude us.
--
Ch. 2 : Science and Hope, p. 28

 
Carl Sagan

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Religious people often say that religion offers absolute certainty about right and wrong; 'god tells them' what it is. Even supposing that the aforementioned gods exist, and that the believers really know what the gods think, that still does not provide certainty, because any being no matter how powerful can still be wrong. Whether gods exist or not, there is no way to get absolute certainty about ethics. Without absolute certainty, what do we do? We do the best we can. Injustice is happening now; suffering is happening now. We have choices to make now. To insist on absolute certainty before starting to apply ethics to life decisions is a way of choosing to be amoral.

 
Richard M. Stallman
 

In our contemporary social and intellectual plight, it is nothing less than shocking to discover that those persons who claim to have discovered an absolute are usually the same people who also pretend to be superior to the rest. To find people in our day attempting to pass off to the world and recommending to others some nostrum of the absolute which they claim to have discovered is merely a sign of the loss of and the need for intellectual and moral certainty, felt by broad sections of the population who are unable to look life in the face.

 
Karl Mannheim
 

The thing we must do intensely is be human together. People are more important than things. We must get together. The best thing humans can have going for them is each other. We have each other. We must reject everything which humiliates us. Humans are not objects of consumption.
We must develop an absolute priority of humans ahead of profit — any humans ahead of any profit. Then we will survive. …
Together.

 
Frank Herbert
 

The Principle of Uncertainty is a bad name. In science, or outside of it, we are not uncertain; our knowledge is merely confined, within a certain tolerance. We should call it the Principle of Tolerance. And I propose that name in two senses. First, in the engineering sense: Science has progressed, step by step, the most successful enterprise in the ascent of man, because it has understood that the exchange of information between man and nature, and man and man, can only take place with a certain tolerance. But second, I also use the word, passionately, about the real world. All knowledge – all information between human beings – can only be exchanged within a play of tolerance. And that is true whether the exchange is in science, or in literature, or in religion, or in politics, or in any form of thought that aspires to dogma. It's a major tragedy of my lifetime and yours that scientists were refining, to the most exquisite precision, the Principle of Tolerance – and turning their backs on the fact that all around them, tolerance was crashing to the ground beyond repair. The Principle of Uncertainty or, in my phrase, the Principle of Tolerance, fixed once for all the realization that all knowledge is limited. It is an irony of history that at the very time when this was being worked out, there should rise, under Hitler in Germany and other tyrants elsewhere, a counter-conception: a principle of monstrous certainty. When the future looks back on the 1930s, it will think of them as a crucial confrontation of culture as I have been expounding it – the ascent of man against the throwback to the despots' belief that they have absolute certainty.

 
Jacob Bronowski
 

The Principle of Uncertainty is a bad name. In science, or outside of it, we are not uncertain; our knowledge is merely confined, within a certain tolerance. We should call it the Principle of Tolerance. And I propose that name in two senses. First, in the engineering sense: Science has progressed, step by step, the most successful enterprise in the ascent of man, because it has understood that the exchange of information between man and nature, and man and man, can only take place with a certain tolerance. But second, I also use the word, passionately, about the real world. All knowledge – all information between human beings – can only be exchanged within a play of tolerance. And that is true whether the exchange is in science, or in literature, or in religion, or in politics, or in any form of thought that aspires to dogma. It's a major tragedy of my lifetime and yours that scientists were refining, to the most exquisite precision, the Principle of Tolerance – and turning their backs on the fact that all around them, tolerance was crashing to the ground beyond repair. The Principle of Uncertainty or, in my phrase, the Principle of Tolerance, fixed once for all the realization that all knowledge is limited. It is an irony of history that at the very time when this was being worked out, there should rise, under Hitler in Germany and other tyrants elsewhere, a counter-conception: a principle of monstrous certainty. When the future looks back on the 1930s, it will think of them as a crucial confrontation of culture as I have been expounding it – the ascent of man against the throwback to the despots' belief that they have absolute certainty.

 
Jacob Bronowski
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