The day of the last hypothesis would be also the day of the last observation... An hypothesis displaced by new facts dies an honorable death. If it has itself summoned to its trial the facts by which it is annihilated, it deserves even a monument of gratitude.
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Handbook of Rational Pathology, 1846-1853Jacob Henle
(Coining phrase "null hypothesis") In relation to any experiment we may speak of this hypothesis as the “null hypothesis,” and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.
Ronald Fisher
"Have the climate models been successful in predicting anything? They, of course, predict substantial global warming. This is not surprising given the expressed belief of some of the model builders in the global warming hypothesis and the many parameters in the model that need to be introduced. However, the models also predict unambiguously that the atmosphere is warming faster than the surface of the earth; but all the available observational data unambiguously shows the opposite! Truth in science is always determined from observational facts. One finds the truth by making a hypothesis and comparing observations with the hypothesis. It is absolutely essential that one should be neutral and not fall in love with the hypothesis. If the facts are contrary to any predictions, then the hypothesis is wrong no matter how appealing. "Truth by Assertion" is not science."
David Douglass
Mr. Darwin's hypothesis is not, so far as I am aware, inconsistent with any known biological fact; on the contrary, if admitted, the facts of Development, of Comparative Anatomy, of Geographical Distribution, and of Palaeontology, become connected together, and exhibit a meaning such as they never possessed before; and I, for one, am fully convinced that if not precisely true, that hypothesis is as near an approximation to the truth as, for example, the Copernican hypothesis was to the true theory of the planetary motions.
Thomas Henry Huxley
Mr. Darwin's hypothesis is not, so far as I am aware, inconsistent with any known biological fact; on the contrary, if admitted, the facts of Development, of Comparative Anatomy, of Geographical Distribution, and of Palaeontology, become connected together, and exhibit a meaning such as they never possessed before; and I, for one, am fully convinced that if not precisely true, that hypothesis is as near an approximation to the truth as, for example, the Copernican hypothesis was to the true theory of the planetary motions.
Charles Darwin
It is possible to express the laws of thermodynamics in the form of independent principles, deduced by induction from the facts of observation and experiment, without reference to any hypothesis as to the occult molecular operations with which the sensible phenomena may be conceived to be connected; and that course will be followed in the body of the present treatise. But, in giving a brief historical sketch of the progress of thermodynamics, the progress of the hypothesis of thermic molecular motions cannot be wholly separated from that of the purely inductive theory.
William John Macquorn Rankine
Henle, Jacob
Henley, Don
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