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As scientific men we have all, no doubt, felt that our fellow men have become more and more satisfying as fish have taken up their work which has been put often to base uses, which must lead to disaster. But what sin is to the moralist and crime to the jurist so to the scientific man is ignorance. On our plane knowledge and ignorance are the immemorial adversaries.
Scientific men can hardly escape the charge of ignorance with regard to the precise effect of the impact of modern science upon the mode of living of the people and upon their civilisation. For them, such a charge is worse than that of crime.
--
Frederick Soddy's speech at the Nobel Banquet in Stockholm, December 10, 1922.

 

Frederick Soddy

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Ever since the beginning of modern science, the best minds have recognized that "the range of acknowledged ignorance will grow with the advance of science." "In science the more we know, the more extensive the contact with nescience." Unfortunately, the popular effect of this scientific advance has been a belief, seemingly shared by many scientists, that the range of our ignorance is steadily diminishing and that we can therefore aim at more comprehensive and deliberate control of all human activities. It is for this reason that those intoxicated by the advance of knowledge so often become the enemies of freedom … The more men know, the smaller the share of all that knowledge becomes that any one mind can absorb. The more civilized we become, the more relatively ignorant must each individual be of the facts on which the working of his civilization depends.

 

Friedrich Hayek

 

Up until the publication of Thomas Kuhn's The Structure of Scientific Revolutions in 1962, the history, philosophy, and sociology of science maintained an internalist approach to scientific knowledge claims. Science was seen as somehow above any social, political, or cultural influences, and therefore, the examinations of scientific knowledge focused on areas such as 'discoveries,' 'famous men,' and 'the scientific revolution in the West.' When Kuhn opened the door to the possibility that external factors were involved in the development of scientific paradigms, science studies assumed a more critical tone.

 

Thomas Samuel Kuhn

 

The scientist has a lot of experience with ignorance and doubt and uncertainty, and this experience is of very great importance, I think. When a scientist doesn’t know the answer to a problem, he is ignorant. When he has a hunch as to what the result is, he is uncertain. And when he is pretty damn sure of what the result is going to be, he is still in some doubt. We have found it of paramount importance that in order to progress, we must recognize our ignorance and leave room for doubt. Scientific knowledge is a body of statements of varying degrees of certainty — some most unsure, some nearly sure, but none absolutely certain. Now, we scientists are used to this, and we take it for granted that it is perfectly consistent to be unsure, that it is possible to live and not know. But I don’t know whether everyone realizes this is true. Our freedom to doubt was born out of a struggle against authority in the early days of science. It was a very deep and strong struggle: permit us to question — to doubt — to not be sure. I think that it is important that we do not forget this struggle and thus perhaps lose what we have gained.

 

Richard Feynman

 

Montaigne speak of an “Abecedarian” ignorance that precedes knowledge, and a doctoral ignorance that comes after it. The first is the ignorance of those who, not knowing their A-B-C’s, cannot read at all. The second is the ignorance of those who have misread many books.

 

Michel de Montaigne

 

When grown people speak of the innocence of children, they dont really know what they mean. Pressed, they will go a step further and say, Well, ignorance then. The child is neither. There is no crime which a boy of eleven had not envisaged long ago. His only innocence is, he may not be old enough to desire the fruits of it, which is not innocence but appetite; his ignorance is, he does not know how to commit it, which is not ignorance but size. But Boon didn't know this. He must seduce me. And he had so little time: only from the time the train left until dark.

 

William Faulkner