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The centermost processes of the brain with which consciousness is presumably associated are simply not understood. They are so far beyond our comprehension that no one I know of has been able to imagine their nature.
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As quoted in Genius Talk : Conversations with Nobel Scientists and Other Luminaries (1995) by Denis Brian ISBN 0306450895

 

Roger Wolcott Sperry

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There is one aspect of our own mentality for which it's difficult as yet to foresee what type of explanation would even be relevant. I'm referring, of course, to consciousness. The point is that although I have no reason to believe that my consciousness is implemented by anything other than my brain, I remain convinced that there's something impenetrably mysterious about the relationship between brains and thoughts. And you can understand, therefore, why it's so hard to imagine, let alone tolerate, the idea that the death of the brain necessarily leads to the end of the personal self – and this, of course, is the "trump card" with which religion has consistently played.

 

Jonathan Miller

 

As a brain researcher, I'd started out simply accepting the strictly objective principles of the behaviorist position. In the 1950s and early 1960s, all respectable neuroscientists thought in these terms. In those days, we wouldn't have been caught dead implying that consciousness or subjective experience can affect physical brain processing.
My first break with this thinking — although I certainly didn't see it that way at the time — came in a 1952 discussion of mind-brain theory in which I proposed a fundamentally new way of looking at consciousness. In it, I suggested that when we focus consciously on an object — and create a mental image for example — it's not because the brain pattern is a copy or neural representation of the perceived object, but because the brain experiences a special kind of interaction with that object, preparing the brain to deal with it.
I maintained that an identical feeling or thought on two separate occasions did not necessarily involve the identical nerve cells each time. Instead, it is the operational impact of the neural activity pattern as a whole that counts, and this depends on context — just as the word "lead" can mean different things, depending on the rest of the sentence.

 

Roger Wolcott Sperry

 

He had a mystical philosophy of "blood" which I disliked. "There is," he said, "another seat of consciousness than the brain and nerves. There is a blood consciousness which exists in us independently of the ordinary mental consciousness. One lives, knows and has one's being in the blood, without any reference to nerves and brain. This is one half of life belonging to the darkness. When I take a woman, then the blood percept is supreme. My blood knowing is overwhelming. We should realize that we have a blood being, a blood consciousness, a blood soul complete and apart from a mental and nerve consciousness." This seemed to me frankly rubbish, and I rejected it vehemently, though I did not then know that it led straight to Auschwitz.

 

D. H. Lawrence

 

However, many applied optimization problems have not been considered yet. It is necessary to use optimization methods of quantum and bio-molecular systems, because of the practical importance of the implementation of physical processes satisfying the required quality criteria. Most of the attention is focused on the following problems: … 2. Mathematical modeling of controlled physical and chemical processes in the brain; [to] consider the brain as a quantum macroscopic object (Gomatam, 1999).

 

Ravi Gomatam

 

One of the more important things to come out of the split-brain work, as an indirect spin-off, is a revised concept of the nature of consciousness and its fundamental relation to brain processing. The key development here is a switch from prior non-causal, parallelist views to a new causal, or "interactionist" interpretation that ascribes to inner experience an integral causal control role in brain function and behavior. In effect, and without resorting to dualist views, the mental forces and properties of the conscious mind are restored to the brain of objective science from which they had long been excluded on materialist-behaviorist principles.

 

Roger Wolcott Sperry