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It's strange how the simple things in life go on while we become more difficult.

 

Richard Brautigan

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I told you that your dream was a difficult one. It's the simple things in life that are the most extraordinary; only wise men are able to understand them.

 

Paulo Coelho

 

Must be a strange life these days, for toes. A simple twist of fate and they could have been the big boys, the much-feted opposables, spending their days busy carrying things and controlling machinery and touching interesting parts of people's bodies. They don't get to do any of that. Instead they just get pushed into small, dark leather places and forgotten about, and when they're let free they often seem little more than a strange fringe on the ends of your feet.

 

Michael Marshall Smith

 

In the case of the cosmos, [...] even if we don’t understand how it came about, it’s not helpful to postulate a creator, because the creator is the very kind of thing that needs an explanation - and although it's difficult enough to explain how a very simple origin of the universe came into being - how matter and energy, how one or two physical constants came into existence - although it’s difficult enough to think how simplicity came into existence, it’s a hell of a lot harder to think how something as complicated as a God comes into existence - difficult enough to think of how a deist God comes into existence, and even more difficult to think of - how a Christian God, who actually cares about things like sin and gets Himself born of a virgin.

 

Richard Dawkins

 

A stranger here
Strange things doth meet, strange glories see;
Strange treasures lodg'd in this fair world appear,
Strange all and new to me;
But that they mine should be who nothing was,
That strangest is of all; yet brought to pass.

 

Thomas Traherne

 

What is found in biology is mechanisms, mechanisms built with chemical components and that are often modified by other, later, mechanisms added to the earlier ones. While Occam's razor is a useful tool in the physical sciences, it can be a very dangerous implement in biology. It is thus very rash to use simplicity and elegance as a guide in biological research. While DNA could be claimed to be both simple and elegant, it must be remembered that DNA almost certainly originated fairly close to the origin of life when things were necessarily simple or they would not have got going.
Biologists must constantly keep in mind that what they see was not designed, but rather evolved. It might be thought, therefore, that evolutionary arguments would play a large part in guiding biological research, but this is far from the case. It is difficult enough to study what is happening now. To figure out exactly what happened in evolution is even more difficult. Thus evolutionary achievements can be used as hints to suggest possible lines of research, but it is highly dangerous to trust them too much. It is all too easy to make mistaken inferences unless the process involved is already very well understood.

 

Francis Crick