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There is no logical impossibility in the hypothesis that the world sprang into being five minutes ago, exactly as it then was, with a population that "remembered" a wholly unreal past. There is no logically necessary connection between events at different times; therefore nothing that is happening now or will happen in the future can disprove the hypothesis that the world began five minutes ago.
--
The Analysis of Mind (1921), Lecture IX: Memory, p. 159

 

Bertrand Russell

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(Coining phrase "null hypothesis") In relation to any experiment we may speak of this hypothesis as the “null hypothesis,” and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.

 

Ronald Fisher

 

"Television is to news as a bumper sticker is to Shakespeare. I remember hearing an analogy once that went something like that. Your typical nightly, 35-minute TV news broadcast is a headline service with pictures. Five minutes of police-blotter reporting - fires, murders, car accidents, etc. - five minutes of human-interest stories and small talk, five minutes of weather, five minutes of sports, ten minutes of commercials, and maybe a minute or two for business, science, politics, and affairs of the world."

 

Mike Rosen

 

The hypothesis of God is a peculiar one, in that it supposes an infinitely incomprehensible object, although every hypothesis, as such, supposes its object to be truly conceived in the hypothesis. This leaves the hypothesis but one way of understanding itself; namely, as vague yet as true so far as it is definite, and as continually tending to define itself more and more, and without limit. The hypothesis, being thus itself inevitably subject to the law of growth, appears in its vagueness to represent God as so, albeit this is directly contradicted in the hypothesis from its very first phase. But this apparent attribution of growth to God, since it is ineradicable from the hypothesis, cannot, according to the hypothesis, be flatly false. Its implications concerning the Universes will be maintained in the hypothesis, while its implications concerning God will be partly disavowed, and yet held to be less false than their denial would be. Thus the hypothesis will lead to our thinking of features of each Universe as purposed; and this will stand or fall with the hypothesis. Yet a purpose essentially involves growth, and so cannot be attributed to God. Still it will, according to the hypothesis, be less false to speak so than to represent God as purposeless.

 

Charles Sanders Peirce

 

The notions about the benefits of transgression in my last three novels are not ones I want to see fulfilled. Rather, they are extreme possibilities that may be forced into reality by the suffocating pressures of the conformist world we inhabit. Boredom and a deadening sense of total pointlessness seem to drive a lot of meaningless crimes, from the Hungerford and Columbine shootings to the Dando murder, and there have been dozens of similar crimes in the US and elsewhere over the past 30 years.
These meaningless crimes are much more difficult to explain than the 9/11 attacks, and say far more about the troubled state of the western psyche. My novels offer an extreme hypothesis which future events may disprove — or confirm. They're in the nature of long-range weather forecasts.

 

J. G. Ballard

 

There is a familiar trio of reactions by scientists to a purportedly radical hypothesis: (a) "You must be out of your mind!", (b) "What else is new? Everybody knows that!", and, later - if the hypothesis is still standing - (c) "Hmm. You *might* be on to something!" Sometimes these phases take years to unfold, one after another, but I have seen all three emerge in near synchrony in the course of a half-hour's heated discussion following a conference paper.

 

Daniel C. Dennett