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Ronald Fisher

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Professor Eddington has recently remarked that 'The law that entropy always increases — the second law of thermodynamics — holds, I think, the supreme position among the laws of nature'. It is not a little instructive that so similar a law [the fundamental theorem of natural selection] should hold the supreme position among the biological sciences.
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On the fundamental theorem of natural selection, Ch. 2, p. 36

 
Ronald Fisher

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The law that entropy always increases, holds, I think, the supreme position among the laws of Nature. If someone points out to you that your pet theory of the universe is in disagreement with Maxwell's equations — then so much the worse for Maxwell's equations. If it is found to be contradicted by observation — well, these experimentalists do bungle things sometimes. But if your theory is found to be against the second law of thermodynamics I can give you no hope; there is nothing for it but to collapse in deepest humiliation.

 
Arthur Stanley Eddington
 

[The] Third [problem with Darwinism], which I think is overwhelming, and just sort of blows the whole theory of Random Mutation out of the water, is, at least, let me say, raises big questions, that is. Assuming it all did happen by Random Mutation and Natural Selection, where did the laws of gravity come from. Where did the laws of thermodynamics come from? Where did the laws of motion and, of heat come from? Where, I guess that's the same as thermodynamics. Where did all these laws, that make it possible for the universe to function, where did they all come from? Why isn't all just chaos and everything collapsing in on itself and killing everything?

 
Ben Stein
 

Just like a computer, we must remember things in the order in which entropy increases. This makes the second law of thermodynamics almost trivial. Disorder increases with time because we measure time in the direction in which disorder increases. You can’t have a safer bet than that!

 
Stephen Hawking
 

[We are now] in a position to judge of the validity of the objection which has been made, that the principle of Natural Selection depends on a succession of favourable chances. The objection is more in the nature of an innuendo than of a criticism, for it depends for its force upon the ambiguity of the word chance, in its popular uses. The income derived from a Casino by its proprietor may, in one sense, be said to depend upon a succession of favourable chances, although the phrase contains a suggestion of improbability more appropriate to the hopes of the patrons of his establishment. It is easy without any very profound logical analysis to perceive the difference between a succession of favourable deviations from the laws of chance, and on the other hand, the continuous and cumulative action of these laws. It is on the latter that the principle of Natural Selection relies.

 
Ronald Fisher
 

We may consequently state the fundamental theorem of Natural Selection in the form : The rate of increase in fitness of any organism at any time is equal to its genetic variance in fitness at that time.

 
Ronald Fisher
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