Linus Pauling was not always right in his ideas. But my belief is that, in most cases, if somebody is always right in his ideas you find that he does not have much to say. It is an expression of somebody's fertility that he does produce quite a number of ideas, and I think Linus Pauling's score is pretty high... I do not think, as I said earlier, that it is right to discuss the impact of Linus Pauling on molecular biology. Rather, he was one of the founders of molecular biology. It was not that it existed in some way, and he simply made a contribution. He was one of the founders who got the whole discipline going.
--
Francis Crick, "The Impact of Linus Pauling on Molecular Biology" (1995)Linus Pauling
» Linus Pauling - all quotes »
Linus Pauling undoubtedly stands as one of the most influential scientists of the twentieth century.
Linus Pauling
My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure,” I was supposed to have said in my molecular biology days. (I believe I was sailing at the time.) I think that one should approach these problems at all levels, as was done in molecular biology. Classical genetics is, after all, a black-box subject. The important thing was to combine it with biochemistry. In nature hybrid species are usually sterile, but in science the reverse is often true. Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.
Francis Crick
A spectacular anomaly came up with the hydrides of the nonmetals—an ugly bunch, about as inimical to life as one could get. Arsenic and antimony hydrides were very poisonous and smelly; silicon and phosphorous hydrides were spontaneously inflammable. I had made in my lab the hydrides of sulfur (H2S), selenium (H2Se), and tellurium (H2Te), all Group VI elements, all dangerous and vile-smelling gases. The hydride of oxygen, the first Group VI element, one might predict by analogy, would be a foul-smelling, poisonous, inflammable gas, too, condensing to a nasty liquid around ?100°C. And instead it was water, H2O—stable, potable, odorless, benign, and with a host of special, indeed unique properties (its expansion when frozen, its great heat capacity, its capacity as an ionizing solvent, etc.) which made it indispensable to our watery planet, indispensable to life itself. What made it such an anomaly? […] (This question, I found, had only been resolved recently, in the 1930s, with Linus Pauling's delineation of the hydrogen bond.)
Oliver Sacks
Although Pauling was often controversial and was sometimes criticized in both scientific and political arenas, it is incontrovertible that he had a major impact on science, education, and international peace.
Linus Pauling
In biology the Cartesian view of living organisms as machines, constructed from separate parts, still provides the dominant conceptual framework. Although Descartes' simple mechanistic biology could not be carried very far and had to be modified considerably during the subsequent three hundred years, the belief that all aspects of living organisms can be understood by reducing them to their smallest constituents, and by studying the mechanisms through which these interact, lies at the very basis of most contemporary biological thinking. This passage from a current textbook on modern biology is a clear expression of the reductionist credo: 'One of the acid tests of understanding an object is the ability to put it together from its component parts. Ultimately, molecular biologists will attempt to subject their understanding of cell structure and function to this sort of test by trying to synthesize a cell
Fritjof Capra
Pauling, Linus
Paulus, Friedrich
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z