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Henry Savile Clarke

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We will indulge in all those miscellaneous commercial operations, which when conducted on a small scale are called thieving, but a large scale, financing.

 
Henry Savile Clarke

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This has been a long personal endeavor of mine. Twenty-five years ago ... I just fell in love with brains. ... I decided to dedicate my life to it. It has been a long road, it's up and down, it's actually not an easy thing to do, to say I'm going to work on large-scale theories of brain function. It was not something you could do in the 1980s. There was no place you could go. ... Nobody was doing the large-scale theory. That's changed in only recent years and I started my institute, the Redwood Neuroscience Institute, to create a place where you could focus on this problem. And, I think, that's really all it took.

 
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I think every once in a while I feel the need to break my medium... ...if I have been doing a very large painting I like to drop into something in small scale. It is a challenge to go into this size. It is just to hold my own interest, and then each media has its own conditions.

 
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In large-scale strategy you can frighten the enemy not by what you present to their eyes, but by shouting, making a small force seem large, or by threatening them from the flank without warning. These things all frighten. You can win by making best use of the enemy's frightened rhythm.

 
Miyamoto Musashi
 

The emergence of a unified cognitive moment relies on the coordination of scattered mosaics of functionally specialized brain regions. Here we review the mechanisms of large-scale integration that counterbalance the distributed anatomical and functional organization of brain activity to enable the emergence of coherent behaviour and cognition. Although the mechanisms involved in large-scale integration are still largely unknown, we argue that the most plausible candidate is the formation of dynamic links mediated by synchrony over multiple frequency bands.

 
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It is much more difficult to recede from a scale of expenditure once adopted than it is to extend the accustomed scale in response to an accession of wealth.

 
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