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A well-understood and testable hypothesis like sexual selection surely trumps an untestable appeal to the inscrutable caprices of a creator.
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p. 240

 

Jerry Coyne

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God remains a viable hypothesis as the prime mover, however undefinable and untestable that conception may be.

 

E. O. Wilson

 

The hypothesis of God is a peculiar one, in that it supposes an infinitely incomprehensible object, although every hypothesis, as such, supposes its object to be truly conceived in the hypothesis. This leaves the hypothesis but one way of understanding itself; namely, as vague yet as true so far as it is definite, and as continually tending to define itself more and more, and without limit. The hypothesis, being thus itself inevitably subject to the law of growth, appears in its vagueness to represent God as so, albeit this is directly contradicted in the hypothesis from its very first phase. But this apparent attribution of growth to God, since it is ineradicable from the hypothesis, cannot, according to the hypothesis, be flatly false. Its implications concerning the Universes will be maintained in the hypothesis, while its implications concerning God will be partly disavowed, and yet held to be less false than their denial would be. Thus the hypothesis will lead to our thinking of features of each Universe as purposed; and this will stand or fall with the hypothesis. Yet a purpose essentially involves growth, and so cannot be attributed to God. Still it will, according to the hypothesis, be less false to speak so than to represent God as purposeless.

 

Charles Sanders Peirce

 

The human brain became large by natural selection (who knows why, but presumably for good cause). Yet surely most “things” now done by our brains, and essential both to our cultures and to our very survival, are epiphenomena of the computing power of this machine, not genetically grounded Darwinian entities created specifically by natural selection for their current function.

 

Stephen Jay Gould

 

Let spades be trumps! she said, and trumps they were.

 

Alexander Pope

 

(Coining phrase "null hypothesis") In relation to any experiment we may speak of this hypothesis as the “null hypothesis,” and it should be noted that the null hypothesis is never proved or established, but is possibly disproved, in the course of experimentation. Every experiment may be said to exist only in order to give the facts a chance of disproving the null hypothesis.

 

Ronald Fisher