The job of theorists, especially in biology, is to suggest new experiments. A good theory makes not only predictions, but surprising predictions that then turn out to be true. (If its predictions appear obvious to experimentalists, why would they need a theory?)
Francis Crick
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Any physical theory is always provisional, in the sense that it is only a hypothesis: you can never prove it. No matter how many times the results of experiments agree with some theory, you can never be sure that the next time the result will not contradict the theory. On the other hand, you can disprove a theory by finding even a single observation that disagrees with the predictions of the theory. As philosopher of science Karl Popper has emphasized, a good theory is characterized by the fact that it makes a number of predictions that could in principle be disproved or falsified by observation. Each time new experiments are observed to agree with the predictions the theory survives, and our confidence in it is increased; but if ever a new observation is found to disagree, we have to abandon or modify the theory.
Stephen Hawking
The Steady State theory was what Karl Popper would call a good scientific theory: it made definite predictions, which could be tested by observation, and possibly falsified. Unfortunately for the theory, they were falsified.
Stephen Hawking
Four predictions of the Big Bang Theory have now been verified - surely enough to quench even the most biased critics.
Joseph Silk
The Marxist theory of history, in spite of the serious efforts of some of its founders and followers, ultimately adopted this soothsaying practice [of evading testability]. In some of its earlier formulations (for example in Marx's analysis of the character of the 'coming social revolution') their predictions were testable, and in fact falsified. Yet instead of accepting the refutations the followers of Marx re-interpreted both the theory and the evidence in order to make them agree. In this way they rescued the theory from refutation; but they did so at the price of adopting a device which made it irrefutable. They thus gave a 'conventionalist twist' to the theory; and by this stratagem they destroyed its much advertised claim to scientific status.
Karl Marx
I accept that climate change is a challenge, I accept the broad theory about global warming. I am sceptical about a lot of the more gloomy predictions.
John Howard
Crick, Francis
Crichton, Michael
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