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If Fermi had been born a few years earlier, one could well imagine him discovering Rutherford's atomic nucleus, and then developing Bohr's theory of the hydrogen atom. If this sounds like hyperbole, anything about Fermi is likely to sound like hyperbole.
--
C. P. Snow

 

Enrico Fermi

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We were able to discover two new kinds of atomic species, one was hydrogen of mass 3, unknown until that time, and the other helium of mass 3, also unknown. … We were able to show that heavy hydrogen nuclei, that is to say the cores of heavy hydrogen atoms, could be made to react with one another to produce a good deal of energy and new kinds of atom. …Of course, we had no idea whatever that this would one day be applied to make hydrogen bombs. Our curiosity was just curiosity about the structure of the nucleus of the atom, and the discovery of these reactions was purely, as the Americans would put it, coincidental.

 

Mark Oliphant

 

"During Alfvén's visit he gave a lecture at the University of Chicago, which was attended by Enrico Fermi. As Alfvén described his work, Fermi nodded his head and said, 'Of course.' The next day the entire world of physics said. 'Oh. of course.'"

 

Hannes Alfven

 

However the development proceeds in detail, the path so far traced by the quantum theory indicates that an understanding of those still unclarified features of atomic physics can only be acquired by foregoing visualization and objectification to an extent greater than that customary hitherto. We have probably no reason to regret this, because the thought of the great epistemological difficulties with which the visual atom concept of earlier physics had to contend gives us the hope that the abstracter atomic physics developing at present will one day fit more harmoniously into the great edifice of Science.

 

Werner Heisenberg

 

Heisenberg's name will always be associated with his theory of quantum mechanics, published in 1925, when he was only 23 years old. For this theory and the applications of it which resulted especially in the discovery of allotropic forms of hydrogen, Heisenberg was awarded the Nobel Prize for Physics for 1932.
His new theory was based only on what can be observed, that is to say, on the radiation emitted by the atom. We cannot, he said, always assign to an electron a position in space at a given time, nor follow it in its orbit, so that we cannot assume that the planetary orbits postulated by Niels Bohr actually exist. Mechanical quantities, such as position, velocity, etc. should be represented, not by ordinary numbers, but by abstract mathematical structures called "matrices" and he formulated his new theory in terms of matrix equations.

 

Werner Heisenberg

 

Bohr had... discovered that the frequencies corresponding to very large integers could be calculated accurately from the classical mechanics; they were simply the number of times that an ordinary electron would complete the circuit of its orbit in one second when it was at a very great distance from the nucleus of the atom to which it belonged. This could only mean that when an electron receded to a great distance from the nucleus of its atom, it not only assumed the properties of an ordinary electron, but also behaved as directed by the classical mechanics. Yet the classical mechanics failed completely for the calculation of frequencies corresponding to small orbits.

 

James Jeans