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Dorothy Hodgkin

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One's tendency when one is young is to do experiments just to see what will happen, without really looking for specific things at all. I first set up a little laboratory in the attic at home just to grow crystals or try experiments described in books, such as adding a lot of concentrated sulfuric acid to the blood from a nosebleed which precipitates hemotin from the hemoglobin in the blood. That was quite a nice experiment. I still remember it.
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interviewed by Olivia Cox-Fill (1996). For our daughters: how outstanding women worldwide have balanced home and career. Greenwood Publishing Group. p. 171. ISBN 0-275-95199-5. 

 
Dorothy Hodgkin

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All experiments in psychology are not of this [cargo cult] type, however. For example there have been many experiments running rats through all kinds of mazes, and so on — with little clear result. But in 1937 a man named Young did a very interesting one. He had a long corridor with doors all along one side where the rats came in, and doors along the other side where the food was. He wanted to see if he could train rats to go to the third door down from wherever he started them off. No. The rats went immediately to the door where the food had been the time before.
The question was, how did the rats know, because the corridor was so beautifully built and so uniform, that this was the same door as before? Obviously there was something about the door that was different from the other doors. So he painted the doors very carefully, arranging the textures on the faces of the doors exactly the same. Still the rats could tell. Then he thought maybe they were smelling the food, so he used chemicals to change the smell after each run. Still the rats could tell. Then he realized the rats might be able to tell by seeing the lights and the arrangement in the laboratory like any commonsense person. So he covered the corridor, and still the rats could tell.
He finally found that they could tell by the way the floor sounded when they ran over it. And he could only fix that by putting his corridor in sand. So he covered one after another of all possible clues and finally was able to fool the rats so that they had to learn to go to the third door. If he relaxed any of his conditions, the rats could tell.
Now, from a scientific standpoint, that is an A-number-one experiment. That is the experiment that makes rat-running experiments sensible, because it uncovers the clues that the rat is really using — not what you think it's using. And that is the experiment that tells exactly what conditions you have to use in order to be careful and control everything in an experiment with rat-running.
I looked into the subsequent history of this research. The next experiment, and the one after that, never referred to Mr. Young. They never used any of his criteria of putting the corridor on sand, or of being very careful. They just went right on running rats in the same old way, and paid no attention to the great discoveries of Mr. Young, and his papers are not referred to, because he didn't discover anything about rats. In fact, he discovered all the things you have to do to discover something about rats. But not paying attention to experiments like that is a characteristic of cargo cult science.

 
Richard Feynman
 

Men that are men again: Who goes home?
Tocsin and trumpeter! Who goes home?
For there's blood on the grass and blood on the foam,
And blood on the body, when Man comes home.
And a voice valedictory: Who is for victory?
Who is for liberty?
Who goes home?

 
Gilbert Keith Chesterton
 

ALL THIS IS A DREAM. Still examine it by a few experiments. Nothing is too wonderful to be true, if it be consistent with the laws of nature; and in such things as these experiment is the best test of such consistency.

 
Michael Faraday
 

It is not my purpose to attempt a real autobiography. I simply want to tell the story of my experiments with truth...as my life consists of nothing but those experiments.

 
Mohandas Karamchand (Mahatma) Gandhi
 

History of science played a very important role for me. Before I knew well how to do an experiment, I knew why Joliot has missed the neutron, why his wife missed the fission, why they succeeded in having artificial radioactivity, and even why they almost missed the other things, by doing very nice experiments, but didn't come to the conclusion. That is science. Science is doubt, is research. It is not something which is – and that is the danger of teaching – which is too academic and which the people explain you it is like the logic thing that comes out of the computer, which is not true. You have intuition, you have passion.

 
Georges Charpak
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