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There is nothing new to be discovered in physics now. All that remains is more and more precise measurement.
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Although reportedly from an address to the British Association for the Advancement of Science (1900), the quote is only duplicated without citation to any primary source in various books, including Superstring : A theory of everything? (1988) by Paul Davies and Julian Brown; also in Rebuilding the Matrix : Science and Faith in the 21st Century (2003) by Denis Alexander. To be more credible, a source prior to the 1980s and close to 1900 is needed.
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Confusion may be due to Michelson who made a similar quote whilst mentioning Lord Kelvin: In 1894, Albert A. Michelson remarked that in physics there were no more fundamental discoveries to be made. Quoting Lord Kelvin, he continued, “An eminent physicist remarked that the future truths of physical science are to be looked for in the sixth place of decimals.

 

William - a.k.a. Lord Kelvin Thomson

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The more precise the measurement of position, the more imprecise the measurement of momentum, and vice versa.

 

Werner Heisenberg

 

I just want to explain what I mean when I say that we should try to hold on to physical reality.
We are ... all aware of the situation regarding what will turn out to be the basic foundational concepts in physics: the point-mass or the particle is surely not among them; the field, in the Faraday-Maxwell sense, might be, but not with certainty. But that which we conceive as existing ("real") should somehow be localized in time and space. That is, the real in one part of space, A, should (in theory) somehow "exist" independently of that which is thought of as real in another part of space, B. If a physical system stretches over A and B, then what is present in B should somehow have an existence independent of what is present in A. What is actually present in B should thus not depend the type of measurement carried out in the part of space A; it should also be independent of whether or not a measurement is made in A.
If one adheres to this program, then one can hardly view the quantum-theoretical description as a complete representation of the physically real. If one attempts, nevertheless, so to view it, then one must assume that the physically real in B undergoes a sudden change because of a measurement in A. My physical instincts bristle at that suggestion.
However, if one renounces the assumption that what is present in different parts of space has an independent, real existence, then I don't see at all what physics is supposed to be describing. For what is thought to be a "system" is after all, just conventional, and I do not see how one is supposed to divide up the world objectively so that one can make statements about parts.

 

Albert Einstein

 

The concept of 'measurement' becomes so fuzzy on reflection that it is quite surprising to have it appearing in physical theory at the most fundamental level... does not any analysis of measurement require concepts more fundamental than measurement? And should not the fundamental theory be about these more fundamental concepts?

 

John Stewart Bell

 

During many ages there were witches. The Bible said so. the Bible commanded that they should not be allowed to live. Therefore the Church, after eight hundred years, gathered up its halters, thumb-screws, and firebrands, and set about its holy work in earnest. She worked hard at it night and day during nine centuries and imprisoned, tortured, hanged, and burned whole hordes and armies of witches, and washed the Christian world clean with their foul blood. Then it was discovered that there was no such thing as witches, and never had been. One does not know whether to laugh or to cry. Who discovered that there was no such thing as a witch—the priest, the parson? No, these never discover anything. … There are no witches. The witch text remains; only the practice has changed. Hell fire is gone, but the text remains. Infant damnation is gone, but the text remains. More than two hundred death penalties are gone from the law books, but the texts that authorized them remain.

 

Mark Twain