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Robert Andrews Millikan

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Science walks forward on two feet, namely theory and experiment.
--
1923 Nobel Prize lecture G๖sta Ekspong, Nobel Foundation (2002). Physics: Nobel Lectures. World Scientific. p. 54. ISBN 9-810-23402-3. 

 
Robert Andrews Millikan

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In science, conjecture drives both experiment and theory for it is only by forming conjectures (hypotheses) that we can make the direction of our experiments and theories informed. If such and such is true, then I should be able to do this experiment and look for this particular result or I should be able to find this theoretical formulation. Conversely, experiment and theory drive conjecture. One makes a startling observation or has a sudden insight and begins to speculate on its significance and implications and to draw possible conclusions (conjecture).

 
Robert Curl
 

Why is Einstein's theory better than Lorentz's theory? It would be a mistake to argue that Einstein's theory gives an explanation of Michelson's experiment, since it does not do so. Michelson's experiment is simply taken over as an axiom.

 
Hans Reichenbach
 

"Incidentally, psycho-analysis is not a science: it is at best a medical process, and perhaps even more like witch-doctoring. It has a theory as to what causes disease - lots of different "spirits" etc. The witch doctor has a theory that a disease like malaria is caused by a spirit which comes into the air ; it is not cured by shaking a snake over it, but quinine does help malaria. So, if you are sick, I would advise that you go to the witch doctor because he is the man in the tribe who knows the most about the disease; on the other hand his knowledge is not science. Psychoanalysis has not been checked carefully by experiment... (page 63)

 
Richard Feynman
 

There is one feature I notice that is generally missing in "cargo cult science." It's a kind of scientific integrity, a principle of scientific thought that corresponds to a kind of utter honesty — a kind of leaning over backwards. For example, if you're doing an experiment, you should report everything that you think might make it invalid — not only what you think is right about it; other causes that could possibly explain your results; and things you thought of that you've eliminated by some other experiment, and how they worked — to make sure the other fellow can tell they have been eliminated.
Details that could throw doubt on your interpretation must be given, if you know them. You must do the best you can — if you know anything at all wrong, or possibly wrong — to explain it. If you make a theory, for example, and advertise it, or put it out, then you must also put down all the facts that disagree with it, as well as those that agree with it. There is also a more subtle problem. When you have put a lot of ideas together to make an elaborate theory, you want to make sure, when explaining what it fits, that those things it fits are not just the things that gave you the idea for the theory; but that the finished theory makes something else come out right, in addition.
In summary, the idea is to try to give all of the information to help others to judge the value of your contribution; not just the information that leads to judgment in one particular direction or another.

 
Richard Feynman
 

That, at any rate, is the theory of our Constitution. It is an experiment, as all life is an experiment.

 
Oliver Wendell Holmes
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