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There are many reasons, some of them so deep-seated emotionally as to be very difficult of expression. Possibly the simplest explanation is that we started along this road ... and I cannot stop until I have won.
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Her reason for flying as explained to her father
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Quoted in Shayler, David J. and Moule, Ian A. (2005). Women in Space — Following Valentina. Springer-Praxis. doi:10.1007/1-84628-078-8_1. ISBN 978-1-84628-078-8. 

 

Jeannette Piccard

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You are always taught to do as much as you can. Always put checks in. Always look for exceptions. Always handle the most general case. Always give the user the best advice. Always print a meaningful error message. Always this. Always that. You have so many things in the background that you're supposed to do, there's no room left to think. I say, forget all that and ask yourself, "What's the simplest thing that could possibly work?"
I think the advice got turned into a command: "Do the simplest thing that could possibly work." That's a little more confusing, because there isn't this notion that as soon as you've done it, we'll evaluate it.

 

Ward Cunningham

 

It's very difficult to explain what I do. It is much more instinctive than you realize; much, much more. ... the reasons that make me interested in a subject are, how shall I say, fickle. Many times I have chosen, among three stories, one for reasons that are entirely accidental: I get up and think this one will be stupendous because the night before I had a certain dream. Or perhaps I put it better by saying that I had found inside myself reasons why this particular story seems more valid. ... I always have motives, but I forget them.

 

Michelangelo Antonioni

 

I never started to plow in my life
That some one did not stop in the road
And take me away to a dance or picnic.
I ended up with forty acres;
I ended up with a broken fiddle —
And a broken laugh, and a thousand memories,
And not a single regret.

 

Edgar Lee Masters

 

In the case of the cosmos, [...] even if we don’t understand how it came about, it’s not helpful to postulate a creator, because the creator is the very kind of thing that needs an explanation - and although it's difficult enough to explain how a very simple origin of the universe came into being - how matter and energy, how one or two physical constants came into existence - although it’s difficult enough to think how simplicity came into existence, it’s a hell of a lot harder to think how something as complicated as a God comes into existence - difficult enough to think of how a deist God comes into existence, and even more difficult to think of - how a Christian God, who actually cares about things like sin and gets Himself born of a virgin.

 

Richard Dawkins

 

I wonder if I could have been here before as I drive up the Roman road the Theater seems familiar — perhaps I headed a legion up that same white road... I passed a chateau in ruins which I possibly helped escalade in the middle ages. There is no proof nor yet any denial. We were, We are, and we will be.

 

George S. Patton