I can’t be as confident about computer science as I can about biology. Biology easily has 500 years of exciting problems to work on. It’s at that level.
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Computer Literacy Bookshops Interview Computer Literacy Bookshops Interview (1993)
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On why bioinformatics is very excitingDonald Knuth
My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure,” I was supposed to have said in my molecular biology days. (I believe I was sailing at the time.) I think that one should approach these problems at all levels, as was done in molecular biology. Classical genetics is, after all, a black-box subject. The important thing was to combine it with biochemistry. In nature hybrid species are usually sterile, but in science the reverse is often true. Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.
Francis Crick
The term "informatics" was first defined by Saul Gorn of University of Pennsylvania in 1983 (Gorn, 1983) as computer science plus information science used in conjunction with the name of a discipline such as business administration or biology. It denotes an application of computer science and information science to the management and processing of data, information and knowledge in the named discipline.
Saul Gorn
[Biology has] become the paramount science, exceeding other disciplines, including physics and chemistry at least, in the creative tumult of its disciplines and disputations. [...] I'll also be so bold at this point to suggest that we are now at the edge of establishing the two fundamental laws of biology: The first law is that all of the phenomena of biology, the entities and the processes, are ultimately obedient to the laws of physics and chemistry. Not immediately reducible to them, but ultimately consistent and in consilience with them, by a cause and effect explanation. The second law is that all biological phenomena, these entities and processes that define life itself, have arisen by evolution through natural selection.
E. O. Wilson
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
Francis Crick
"[Computer science] is not really about computers -- and it's not about computers in the same sense that physics is not really about particle accelerators, and biology is not about microscopes and Petri dishes...and geometry isn't really about using surveying instruments. Now the reason that we think computer science is about computers is pretty much the same reason that the Egyptians thought geometry was about surveying instruments: when some field is just getting started and you don't really understand it very well, it's very easy to confuse the essence of what you're doing with the tools that you use."
Hal Abelson
Knuth, Donald
Kobayashi, Makoto (physicist)
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