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Of course, we must avoid postulating a new element for each new phenomenon. But an equally serious mistake is to admit into the theory only those elements which can now be observed. For the purpose of a theory is not only to correlate the results of observations that we already know how to make, but also to suggest the need for new kinds of observations and to predict their results. In fact, the better a theory is able to suggest the need for new kinds of observations and to predict their results correctly, the more confidence we have that this theory is likely to be good representation of the actual properties of matter and not simply an empirical system especially chosen in such a way as to correlate a group of already known facts.
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(January 15 1952). "A Suggested Interpretation of the Quantum Theory in Terms of "Hidden" Variables. II". Physical Review 35 (2): 189.

 

David Bohm

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Any physical theory is always provisional, in the sense that it is only a hypothesis: you can never prove it. No matter how many times the results of experiments agree with some theory, you can never be sure that the next time the result will not contradict the theory. On the other hand, you can disprove a theory by finding even a single observation that disagrees with the predictions of the theory. As philosopher of science Karl Popper has emphasized, a good theory is characterized by the fact that it makes a number of predictions that could in principle be disproved or falsified by observation. Each time new experiments are observed to agree with the predictions the theory survives, and our confidence in it is increased; but if ever a new observation is found to disagree, we have to abandon or modify the theory.

 

Stephen Hawking

 

If we consider further the manifold relations of this mathematical theory to civil uses and the technical arts, we shall recognize completely the extent of its applications. It is evident that it includes an entire series of distinct phenomena, and that the study of it cannot be omitted without losing a notable part of the science of nature.
The principles of the theory are derived, as are those of rational mechanics, from a very small number of primary facts, the causes of which are not considered by geometers, but which they admit as the results of common observations confirmed by all experiment.

 

Joseph Fourier

 

We shall see that the mathematical treatment of the subject [of electricity] has been greatly developed by writers who express themselves in terms of the 'Two Fluids' theory. Their results, however, have been deduced entirely from data which can be proved by experiment, and which must therefore be true, whether we adopt the theory of two fluids or not. The experimental verification of the mathematical results therefore is no evidence for or against the peculiar doctrines of this theory.

 

James Clerk Maxwell

 

Happily I had very early learned the fallacy of building much on logic and verbal argument. Single sets of truths I knew to be as little conclusive in theology as in physics; and, in one as in the other, no theory to be worth anything, however plausibly backed up with Scripture texts or facts, which was not gathered bona fide from the analysis of all the attainable phenomena, and verified wherever possible by experiment.
"Here is a theory of the world which you bring for my acceptance: well, there is the world; try — will the key fit? can you read the language into sense by it?" was the only method; and so I was led always to look at broad results, at pages and chapters, rather than at single words and sentences, where for a few lines a false key may serve to make a meaning. So of these broad observations I only expected a broad solution.

 

James Anthony Froude

 

That's all window dressing. That's not fundamental. That's not getting at change and the transformation that must take place. Sure we have to solve problems. Certainly stamp out the fire. Stamp out the fire and get nowhere. Stamp out the fires puts us back to where we were in the first place. Taking action on the basis of results without theory of knowledge, without theory of variation, without knowledge about a system. Anything goes wrong, do something about it, overreacting; acting without knowledge, the effect is to make things worse. With the best of intentions and best efforts, managing by results is, in effect, exactly the same, as Dr. Myron Tribus put it, while driving your automobile, keeping your eye on the rear view mirror, what would happen? And that's what management by results is, keeping your eye on results.

 

W. Edwards Deming