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I want to build vast machines of light and darkness, intricate mechanisms within mechanisms, a progression of gears and cogs and pistons each working to its own end as well as that of the Greater Device. That's what I see in my head. But, too often, I sense that many readers want nothing more complex or challenging than wind-up toys. It's dispiriting.
--
(3 January 2005)

 

Caitlin R. Kiernan

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When scientists need to explain difficult points of theory, illustration by hypothetical example - rather than by total abstraction - works well (perhaps indispensably) as a rhetorical device. Such cases do not function as speculations in the pejorative sense - as silly stories that provide insight into complex mechanisms - but rather as idealized illustrations to exemplify a difficult point of theory. (Other fields, like philosophy and the law, use such conjectural cases as a standard device.)

 

Stephen Jay Gould

 

The relationship between information and the mechanisms for its control is fairly simple to describe: Technology increases the available supply of information. ...control mechanisms are strained... When additional control mechanisms are themselves technical, they in turn further increase the supply of information. When the supply of information is no longer controllable, a general breakdown in psychic tranquillity and social purpose occurs. Without defenses, people have no way of finding meaning in their experiences, lose their capacity to remember, and have difficulty imagining reasonable futures.

 

Neil Postman

 

If most of us were wind up-toys, could we trust the few of us that weren't to wind us up when necessary? I think not. We would be a separate oppressed minority. Even if we were in the majority, it would still be that way. The ones that weren't wind-up toys would have the upper hand, and we would have to look out for each other, because they wouldn't.

 

John S. Hall

 

What is found in biology is mechanisms, mechanisms built with chemical components and that are often modified by other, later, mechanisms added to the earlier ones. While Occam's razor is a useful tool in the physical sciences, it can be a very dangerous implement in biology. It is thus very rash to use simplicity and elegance as a guide in biological research. While DNA could be claimed to be both simple and elegant, it must be remembered that DNA almost certainly originated fairly close to the origin of life when things were necessarily simple or they would not have got going.
Biologists must constantly keep in mind that what they see was not designed, but rather evolved. It might be thought, therefore, that evolutionary arguments would play a large part in guiding biological research, but this is far from the case. It is difficult enough to study what is happening now. To figure out exactly what happened in evolution is even more difficult. Thus evolutionary achievements can be used as hints to suggest possible lines of research, but it is highly dangerous to trust them too much. It is all too easy to make mistaken inferences unless the process involved is already very well understood.

 

Francis Crick

 

The emergence of a unified cognitive moment relies on the coordination of scattered mosaics of functionally specialized brain regions. Here we review the mechanisms of large-scale integration that counterbalance the distributed anatomical and functional organization of brain activity to enable the emergence of coherent behaviour and cognition. Although the mechanisms involved in large-scale integration are still largely unknown, we argue that the most plausible candidate is the formation of dynamic links mediated by synchrony over multiple frequency bands.

 

Francisco Varela