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Ronald Fisher

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...it was Darwin’s chief contribution, not only to Biology but to the whole of natural science, to have brought to light a process by which contingencies a priori improbable, are given, in the process of time, an increasing probability, until it is their non-occurrence rather than their occurrence which becomes highly improbable. ... Let the reader ... attempt to calculate the prior probability that a hundred generations of his ancestry in the direct male line should each have left at least one son. The odds against such a contingency as it would have appeared to his hundredth ancestor (about the time of King Solomon) would require for their expression forty- four figures of the decimal notation; yet this improbable event has certainly happened.
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Retrospect of criticisms of the theory of natural selection. In Evolution as a Process, eds. J.S.Huxley, A.C.Hardy and E.B.Ford, London: Allen and Unwin, 1954.

 
Ronald Fisher

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