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David Deutsch

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To say that prediction is the purpose of a scientific theory is to confuse means with ends. It is like saying that the purpose of a spaceship is to burn fuel. ... Passing experimental tests is only one of many things a theory has to do to achieve the real purpose of science, which is to explain the world. (Ch. 1)

 
David Deutsch

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Men follow their sentiments and their self-interest, but it pleases them to imagine that they follow reason. And so they look for, and always find, some theory which, a posteriori, makes their actions appear to be logical. If that theory could be demolished scientifically, the only result would be that another theory would be substituted for the first one, and for the same purpose.

 
Vilfredo Pareto
 

Third Theory.—According to this theory, there is nothing in the whole Universe... that is due to chance; everything is the result of will, intention, and rule. It is a matter of course that he who rules must know. The Mohametan Ashariyah adhere to this theory, notwithstanding evident absurdities implied in it. ...The Ashariyah were therefore compelled to assume that motion and rest of living beings are predestined, and that it is not in the power of a man to do a certain thing or to leave it undone. ...It follows also from this theory, that precepts are perfectly useless, since the people to whom any law is given... can neither do what they are commanded nor abstain from what they are forbidden. ...According to this theory, it must also be assumed that the actions of God have no final cause. All these absurdities are admitted by the Ashariyah for the purpose of saving this theory.

 
Maimonides
 

A theory is only as good as its assumptions. If the premises are false, the theory has no real scientific value. The only scientific criterion for judging the validity of a scientific theory is a confrontation with the data of experience.

 
Maurice Allais
 

There is one feature I notice that is generally missing in "cargo cult science." It's a kind of scientific integrity, a principle of scientific thought that corresponds to a kind of utter honesty — a kind of leaning over backwards. For example, if you're doing an experiment, you should report everything that you think might make it invalid — not only what you think is right about it; other causes that could possibly explain your results; and things you thought of that you've eliminated by some other experiment, and how they worked — to make sure the other fellow can tell they have been eliminated.
Details that could throw doubt on your interpretation must be given, if you know them. You must do the best you can — if you know anything at all wrong, or possibly wrong — to explain it. If you make a theory, for example, and advertise it, or put it out, then you must also put down all the facts that disagree with it, as well as those that agree with it. There is also a more subtle problem. When you have put a lot of ideas together to make an elaborate theory, you want to make sure, when explaining what it fits, that those things it fits are not just the things that gave you the idea for the theory; but that the finished theory makes something else come out right, in addition.
In summary, the idea is to try to give all of the information to help others to judge the value of your contribution; not just the information that leads to judgment in one particular direction or another.

 
Richard Feynman
 

"The issue of 'science' does not intrude itself directly upon the occasion of the performance of a musical work, at least a non-electronically produced work, since—as has been said—there is at least a question as to whether the question as to whether musical composition is to be regarded as a science or not is indeed really a question; but there is no doubt that the question as to whether musical discourse or—more precisely—the theory of music should be subject to the methodological criteria of scientific method and the attendant scientific language is a question, except that the question is really not the normative one of whether it 'should be' or 'must be,' but the factual one that it is, not because of the nature of musical theory, but because of the nature and scope of scientific method and language, whose domain of application is such that if it is not extensible to musical theory, then musical theory is not a theory in any sense in which the term ever has been employed. This should sound neither contentious nor portentous, rather it should be obvious to the point of virtual tautology.”

 
Milton Babbitt
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